PROBABLE ABSENCE OF DIRECT INDUCTION OF BACTERIAL RESISTANCE TO STREPTOMYCIN
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چکیده
منابع مشابه
Comments on bacterial resistance to streptomycin.
Shortly after streptomycin was introduced in the treatment of tuberculosis, two major obstacles to its value as a therapeutic agent became apparent. These were, vestibular damage and development of bacterial resistance. With the reduction in the daily dosage from 2 gm. and higher, to 1 gm. and later to 0.5 gm., serious vestibular damage has been eliminated. However, development of bacterial res...
متن کاملBacterial dissimilation of streptomycin.
Klein, Dolph (Rutgers, The State University, New Brunswick, N. J.), and David Pramer. Bacterial dissimilation of streptomycin. J. Bacteriol. 82:505-510. 1961.-The influence of various nutritional and environmental factors on the dissimilation of streptomycin by a pseudomonad isolated from soil was investigated, and conditions most suitable for growth of the bacterium, in a medium that contained...
متن کاملTransformation of streptococci to streptomycin resistance.
Perry, Dennis (Northwestern University Medical School, Chicago, Ill.) and Hutton D. Slade. Transformation of streptococci to streptomycin resistance. J. Bacteriol. 83:443-449. 1962.-A total of 43 strains of streptococci, belonging to serological groups A, B, C, D, E, F, G, H, K, L, M, N, O, and Q, and three ungroupable strains were exposed to deoxyribonucleic acid (DNA) extracted from streptomy...
متن کاملStreptomycin resistance in a streptomycin-producing microorganism.
Cell-free extracts of Streptomyces bikiniensis contain an adenosine 5'-triphosphate-dependent kinase which inactivates streptomycin (Sm) and dihydrostreptomycin by phosphorylation. The products have been identified as streptomycin 6-phosphate and dihydrostreptomycin 6-phosphate. Activity was not present in logarithmic-phase cells, which were susceptible to 25 mug of Sm per ml. In stationary-pha...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1957
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.73.6.770-777.1957